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عدد المساهمات : 144 السٌّمعَة : 4 date of birth day : 1990-01-23 تاريخ التسجيل : 2009-03-24 العمر : 34 الموقع : www.ziadalzoubi.tk your job : MANAGEMENT
| Subject: Dr.Adeeb Al-Zoubi Thu 1 Dec - 1:06 | |
| PERSONAL DATA Name: Adeeb M. Y. Al-Zoubi Nationality: Jordanian Marital Status: Married Date and Place of Birth: 2/15/1968, Irbid City, Jordan Jordanian National Number: 9681046103 USA Social Security Number: 637-34-4024 Highest Academic Degree: Ph.D., Immunology, University of Illinois at Chicago, 2002
BASIC RESEARCH INTERESTES Identification and characterization of specific populations of stem cells in human and mouse Development of new stem cell purification and harvesting techniques from human tissues Molecular control of cancer cell apoptosis Cancer immunotherapy using tumor-specific lymphocytes
CLINICAL RESEARCH INTERESTES Stem cells transplantation in treatment of human diseases Immune therapy for breast cancer
PROFESSIONAL AFFILIATIONS/MEMBERSHIPS
Founder and Director, Stem Cells of Arabia Network Vice President, International Association of Neurorestoratology Editorial Board Member, Frontiers in Neuroscience Journal Member, American Association for Cancer Research (AACR) Member, International Study Group for Stem Cell Therapy (ISGSCT) Member, Cell Committee, International Association of Neurorestoratology
CERTIFICATIONS Certified Trainer, Cytokine Secretion , Miltenyi Biotec, USA 2003 Certified Trainer, CD34+ Stem Cell Purification, Miltenyi Biotec, Germany 2005 Certified Trainer, CD133+ Stem Cell Purification, Miltenyi Biotec, Germany 2006 Certified Trainer, CD8+ T Cell Depletion, Miltenyi Biotec, Germany 2007 Certified Trainer, Donor Lymphocyte Infusion, Miltenyi Biotec, Germany 2008 Certified Trainer, Flow Cytometry, Miltenyi Biotec, Germany 2009
RECENT ACCOMPLISHMENTS 2006-2010 - Introduction of unique stem cell-based therapies in Middle Eastern Countries 2007 - Establishment of a stem cell research and therapy facility, Amman, Jordan 2007 - Initiation of a clinical trial using stem cells for treatment of spinal cord injuries - Jordan 2008 - Participation in the first case of using purified autologous adult stem cells for treatment of cardiomyopathy in the Arab World - Jordan 2008-2009 - Development of an ex vivo model for differentiation of mouse and human stem cells into neuronal cells lineages, Jordan 2008-Present - Participation in the first clinical trial for using autologous stem cells for treatment of hepatic failure, Egypt 2009 – Founder of Stem Cells of Arabia Network 2009-2010 - Establishment of standardized stem cell treatment for immune deficiencies, Oman 2009-2010 - Initiation of a pilot study for immune therapy of breast cancer, Jordan 2009-Present - Development of an advanced technique for removal of apoptotic sperm prior to IVF procedures, Jordan 2009 – Present – Introduction of the first method in the world for use of autologous stem cells in treatment of male infertility, Jordan 2010 - Initiation of stem cell therapy protocol in Dubai, UAE
PROFESSIONAL EXPERIENCE Assistant Professor in Stem Cells 2011-Present Department of Surgery, University of Illinois at Chicago, College of Medicine in Peoria Peoria, Illinois, USA
Director, Stem Cells of Arabia Network 2009-Present
Assistant Professor in Molecular Immunology and Stem Cells 2007-Present Department of Biotechnology and Genetic Engineering College of Science, Philadelphia University, Amman, Jordan
Scientific Consultant, Stem Cells 2005-2011 Miltenyi Biotec, GmbH, Bergisch Gladbach, Germany
Lecturer in Molecular Immunology 2005-2007 Department of Biotechnology and Genetic Engineering College of Sciences and Arts, Jordan University of Science and Technology, Irbid, Jordan
Technical Product Scientist 2002-2005 Miltenyi Biotec, Inc., Auburn, California, USA
Biology Instructor 1997 - 2004 Robert Morris College, Chicago, Illinois, USA
Research Assistant 1997 - 2001 Department of Microbiology and Immunology College of Medicine, University of Illinois at Chicago, USA
Laboratory Manager/ Research Specialist 1996-97 Cell and Molecular Biology, College of Medicine, University of Illinois at Chicago, USA
Research Specialist 1995-96 Probe R & D, Diagnostic Division, Abbott Laboratories, Abbott Park, Illinois, USA
Clinical Laboratory Trainee 1994-97 Rosalind Franklin University of Health Sciences/Chicago Medical School, IL, USA Teaching/ Research Assistant 1993-94 Department of Biological Sciences, University of North Texas, Denton, Texas, USA Teaching/ Research Assistant 1990-91 Department of Health Sciences, Jordan University of Science & Technology, Irbid City, Jordan
EDUCATION Department of Medical Technology 1986-90 Southwestern University, Cebu City, Philippines Bachelor of Science Degree in Medical Technology (1990) Master program in Biological Sciences 1993 University of North Texas, Denton, Texas, USA Department of Clinical Laboratory Sciences 1994-96 Rosalind Franklin University of Health Sciences/The Chicago Medical School North Chicago, Illinois, USA Master of Science Degree in Clinical Laboratory Sciences (1997) Thesis: Applications of Polymerase Chain Reaction in Beta Thalassemia Diagnosis Department of Microbiology and Immunology 1997-2002 College of Medicine, The University of Illinois at Chicago Chicago, Illinois, USA Doctor of Philosophy Degree in Microbiology and Immunology (2002) Thesis: Differential Effects of Splice Variants of Human IG20 on Tumor Necrosis Factor-Alpha-Induced Apoptosis
SCHOLARSHIPS, AWARDS AND HONORS
Int’l Mandarin Training Award (two awards), NTNU, Taipei, Taiwan, R.O.C. 1992 Excellence in Research Award, Abbott Laboratories, Abbott Park, IL 1996 Graduate College Scholarship, University of Illinois at Chicago (UIC) 1997-2001 Graduate College Fellowship, UIC, Chicago, IL 2000 Shining Star Award-Cytokine Secretion -Miltenyi Biotec, Auburn, CA 2002 Outstanding Researcher Award, Pan Arab Spine Society, Tunisia 2007 Excellence in Nano-Biotechnology Research, United Arab Emirates University, UAE 2008 Stem Cell Research Award, Egyptian Academy of Scientific Research, Egypt 2009 Excellence in Research Award, Philadelphia University, Amman, Jordan 2011
RECENT TRAINING/Workshops Strategies for Effective Negotiation: The Karrass Institute, CA, USA 2004 Molecular Applications of Nano Technology: Bergisch Gladbach, Germany 2005 Magnetic Purification of Hematopoietic Stem Cells: Bergisch Gladbach, Germany 2006 Stem Cells for Non-hematopoietic Applications: Bergisch Gladbach, Germany 2007 Hepatic Regeneration Using Adult Stem Cells, Cairo, Egypt 2008 Stem Cells for Cardiac Diseases: Bergisch Gladbach, Germany 2008 Tissue Engineering and Organ Regeneration, Alexandria, Egypt 2009 Stem Cells for Spinal Cord Repair, Brescia, Italy 2009 Stem Cells in Neuronal Restoration, Beijing, China 2009 Stem Cells in Treatment of Cardiomyopathies, Bath, UK 2009 Organ Regeneration and Tissue Engineering, Korea 2010 Neuronal Restoration Strategies Using Stem Cells, Jordan 2011
PUBLICATIONS Peer Reviewed Papers: Al-Zoubi AM, Efimova EV, Kaithamana S, Martinez O, El-Idrissi MA, Dogan RE, and Prabhakar BS. Contrasting effects of IG20 and its splice isoforms, MADD and DENN-SV, on tumor necrosis factor alpha-induced apoptosis and activation of caspase-8 and -3. J Biol Chem (2001) Dec 14; 276(50): 47202-11. Al-Zoubi AM, Efimova EV, Martinez O, Kaithamana S, Lu SF, Arima T, and Prabhakar BS. IG20, in Contrast to DENN-SV, (MADD Splice Variants) Suppresses Tumor Cell Proliferation, and Enhances their Susceptibility to Apoptosis and Cancer Drugs. Oncogene (2004) 23, 1076-1087. Al-Zoubi A, Jamous M, Khabaz MN, Khaledi R, Al Khateeb M, Al-Zoubi Z. Purification of mouse bone marrow-derived stem cells promotes ex vivo neuronal differentiation. Cell Transplant (2009)19(2):193-202. Epub 2010 Mar 26. Adeeb Al-Zoubi, Mohammad El-Khateeb, Rahaf Al-Zoubi, Shahed AlSarayreh. IL-2 Abrogates MCF7 Cancer Cell-Mediated Inhibition of IFN-g Secretion By T Cells. Submitted for publication. Adeeb Al-Zoubi. A Novel Method for The Analysis and Purification of Viable Antigen-Specific, Cytokine-Secreting Cells. Invited review for Clinical and Applied Immunology Reviews. Manuscript in preparation. Adeeb Al-Zoubi, Abdullah Asal, Bellur Prabhakar, Mohammad El-Khatib. hnRNPK is Involved in Regulating Alternative Splicing IG20 mRNA. Manuscript in preparation. Adeeb Al-Zoubi, Mohammad Jamous, Rana Khaled, Mohammed El-Khateeb. Purification of Mouse Bone Marrow-Derived Sca1+ and Prominin1+ Stem Cells Enhances Ex-vivo Neuronal Differentiation. Accepted, Cell Transplantation, April, 2010. Adeeb Al-Zoubi, Mohammad Jamous, Mohammed El-Khateeb, Emad Jafar, Ziad Al-Zoubi. Transplantation of Purified Autologous CD34+ and CD133+ Stem Cells for Patients with Complete Spinal Cord Injuries: A novel Method for Preserving the Immune Privilege of The CNS. Submitted to Euro Spine Journal.
Abstracts: Adeeb M. Al-Zoubi, Elena V. Efimova, Shashi Kaithamana, Osvaldo Martinez, Bellur S. Prabhakar: Splice Isoforms of Human IG20: Genomic Organization, Tissue Distribution and Differential Effects on TNFa-Induced Apoptosis. Abstract 770.5; FASEB Annual Meeting of Experimental Biology (2002) 16 (5): p-A1083. Elena V. Efimova, Adeeb M. Al-Zoubi, Shashi Kaithamana, Rukiye E. Dogan, Osvaldo Martinez, Bellur S. Prabhakar: Differential Effects of IG20 and Its Splice Isoform, DENN-SV, on Cell Proliferation and Apoptosis. Abstract770.6; FASEB Annual Meeting of Experimental Biology (2002) 16 (5): p-A1083. Abdallah Al-Eweidi Al-Abbadi, Adeeb Al-Zoubi, and Mona Kilani. Stem cell manipulation: Jordan University Hospital experience. The Second International Jordanian Congress of Allergy and Immunology, Amman, Jordan, May-June, 2007 Adeeb Al-Zoubi, Mohammad El-Khateeb, Mona Kilani, Abdallah Al-Eweidi Al-Abbadi. Special Protocols in Stem Cell Purification. The Second International Jordanian Congress of Allergy and Immunology, Amman, Jordan, May-June, 2007 Adeeb Al-Zoubi and Mohammad Jamous. Treatment of Spinal Cord Injuries Using CD271+ Stem Cells. 5th Pan Arab Spine Congress, Tunis, Tunisia, October, 2007. Adeeb M. Al-Zoubi, Abdallah K. Al Asal, Mohammed El-Khateeb. Molecular Control of Cancer Cell Apoptosis by Regulating Alternative Splicing of IG20 pre-mRNA. Proffered talk at the International Conference of The American Association for Cancer Research, 2008. Adeeb M. Al-Zoubi, Rahaf M. Al-Zoubi, Mohammad S. El-Khateeb. MCF7 breast cancer cells inhibit TNF-Α production by CD8+ T cells. Personalized Cancer Medicine/Therapies Conference of The American Association for Cancer Research. 2008. Adeeb Al-Zoubi, Mohammed Jamoos, Ziad Al-Zoubi. Magnetic Purification of CD133+ Pluripotent Stem Cells by Nano-Particles for Treatment of Spinal Cord Injuries. 2nd International Conference on Nanotechnology. November 17-20, 2008, Abu-Dhabi, UAE. A. Al-Zoubi, M. Alexander, B. Prabhakar. Sensitive Purification of Minute Amounts of Messenger RNA Using Nano-Magnetic Beads. 2nd International Conference on Nanotechnology. November 17-20, 2008, Abu-Dhabi, UAE. A. Al-Zoubi, R. Al-Zoubi, M. El-Khateeb. Magnetic Purification of Breast Cancer-Specific Immune Cells By Super Para-Magnetic Nano-Particles. 2nd International Conference on Nanotechnology. November 17-20, 2008, Abu-Dhabi, UAE. A. Al-Zoubi, A. A. Al-Abbdi. Magnetic purification of stem cells in treatment of hemoglobinopathies and hematological malignancies: A Jordan University Experience. 2nd International Conference on Nanotechnology. November 17-20, 2008, Abu-Dhabi, UAE. A. M. Al-Zoubi, A. K. Al Asal, M. El-Khateeb Utilization of super para-magnetic nano particles in discovering new proteins involved in molecular control of cancer cell death. 2nd International Conference on Nanotechnology. November 17-20, 2008, Abu-Dhabi, UAE. Adeeb Al-Zoubi, Mohammed Jamoos, Ziad Al-Zoubi. Utilization of Purified CD133+ Stem Cells for Treatment of Spinal Cord Injuries. 1st Alexandria International Congress on Tissue Engineering. February 13-16, 2009. Alexandria, Egypt. Adeeb Al-Zoubi, Mohammed Jamoos, Ziad Al-Zoubi. Utilization and Safety Considerations of Purified Autologous CD34+ and CD133+ Stem Cells in Treatment of Spinal Cord Injuries. 7th International Symposium on Experimental Spinal Cord Repair and Regeneration. February 19-21, Brescia, Italy. Ziad .M. Al Zoubi, Adeeb Al-Zoubi, Mohammed Jamoos: Treatment of Spinal Cord Injuries Using Purified Stem Cells - A Jordanian Experience. 2nd International Association of Neurorestoratology Annual Conference. April 24-26, 2009. Beijing, China. Adeeb Al-Zoubi. Treatment of Spinal Cord Injuries Using Bone Marrow-Derived CD34+ and CD133+ Stem Cells: A Jordanian Experience. Autologous Stem Cells, Bath, UK, September 20-21, 2009. Adeeb AlZoubi. Stem Cells in Health and Disease. Stem Cells & Regenerative Medicine Asia, Seoul, Korea, October, 2010 Adeeb AlZoubi, Najeeb Layyous. Utilization of Autologous Bone Marrow-Derived Stem Cells in Treatment of Male Infertility, Proceedings of the 5th Joint Annual Conference of The British Royal College of Gynecology and The Jordanian Association of Gynecology, March, 2011, Amman, Jordan. Adeeb AlZoubi. Stem Cells: A global Perspective. Proceedings of the Combined Conference of The International Association of Neurorestoratology (IANR IV), Global College of Neuroprotection & Neuroregeneration GCNN 8th), and American Society for Neural Therapy and Repair (ASNTR) conference. April, 2011, Amman, Jordan.
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